This response to RFA-MH-20-520 (Implementation Research in HRSA Ryan White Sites: Screening and Treatment for Mental and Substance Use Disorders to Further the National “Ending the HIV Epidemic” [EHE] Goals; attached) is motivated in part by one of the RFA’s NIH Project Officer’s strongly encouraging Bryan Garner to submit an application. Additionally, this RFA is perfectly aligned with Bryan’s current program of research, especially Bryan’s Substance Abuse Treatment to HIV care (SAT2HIV Project) that is successfully concluding on 6/30/2020 and the current application would seek to build upon most directly. Per the RFA, “The purpose of this initiative is to enhance screening and treatment for mental and substance use disorders in HRSA Ryan White HIV/AIDS Program funded sites through implementation research, to advance the goals of the ending the HIV epidemic (EHE) initiative. Additionally, the RFA notes “NIH intends to fund an estimate of 4-6 awards.”