Project Description

The proposed Diversity Supplement to R01 HD094629 will contribute to the parent study by examining pregnancy outcomes of AGYW using PrEP and the factors influencing PrEP use during pregnancy. The study will use a mixed-methods design. All AGYW using PrEP who test positive for pregnancy at baseline, 3-, 6-, or 9-month follow-up will be contacted by study staff and asked to consent to be tracked for pregnancy outcomes up to 8 weeks post-partum. Those who consent to tracking will be contacted monthly for a brief check-in call to assess PrEP use. During the post-partum period, a purposive sample of AGYW will be asked to complete an in-depth interview with study staff to explore the factors that influenced their decision to maintain or discontinue PrEP use during pregnancy. In-depth interviews will also be conducted with providers to assess their attitudes, beliefs, and medical recommendations regarding AGYW PrEP use during pregnancy. The proposed aims are: Aim 1: To compare pregnancy outcomes (i.e. number of AGYW who become pregnant, number who terminate pregnancies, and the infant outcomes) between AGYW who use PrEP and those who do not use PrEP. Aim 2: To compare PrEP uptake and adherence between AGYW who become pregnant ant those who do not become pregnant Aim 3: Among pregnant AGYW using PrEP, explore the factors that influence AGYW’s decision to maintain or discontinue PrEP use Aim 4: Explore provider attitudes and beliefs toward AGYW who are pregnant and use PrEP and the medical recommendations they make regarding PrEP using during pregnancy.

Key Staff
Project Coordinator
Project Partners
PHS NIH NICHD
Project Open
Closed
Countries