Project Description

This project is a secondary study to the Transfusion of Prematures (TOP). The TOP Trial hypothesizes that maintaining higher hemoglobin levels in extremely low birth weight (ELBW) infants by use of a high hemoglobin threshold for transfusion will lead to a higher rate of survival without neurodevelopmental impairment. This secondary proposal enhances the TOP trial through assessment of regional tissue oxygenation of the brain and gastrointestinal tract using bedside near-infrared spectroscopy (NIRS) monitoring.

Project Partners
NIH National Heart, Lung, and Blood Institute|Stanford University|
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