RTI International conducted a participatory process evaluation with three programs [Standing Against Global Exploitation (SAGE) Project, Inc., The Salvation Army Trafficking Outreach Program and Intervention Techniques (STOP-IT), and The Streetwork Project at Safe Horizon] that provided comprehensive services to male, female, and transgender domestic minor victims of human trafficking. The service programs were funded by the U.S. Department of Justice, Office for Victims of Crime (OVC) and collectively served 201 young people during the study period (January 2011 through June 2013). The process evaluation focused on describing program operations and implementation experiences as the groundwork for refinement of program models and evaluation strategies. The goal of this project was to generate much-needed information on the trafficking of minors, including the characteristics and needs of youths who are victims of sex and labor trafficking. Findings from the evaluation identified promising practices in the delivery of comprehensive services to best meet the needs of trafficked youths.