The project is designed to address the gap between research and practice. Over the course of the project, RTI staff has developed, tested, and refined marketing and implementation strategies for integrating the Women’s Health CoOp (WHC) into clinics that provide HIV counseling and testing (HCT) and antenatal care, as well as into rehab programs. WHC is a woman-focused, behavioral prevention intervention for vulnerable women who use alcohol or drugs. The specific aims of this study include the following: (1) Develop, implement, and assess the appropriateness of a marketing plan to facilitate entry into health and rehab clinics for the implementation of the WHC; (2) Deliver the WHC via a stepped-wedge design across health and rehab clinics to evaluate implementation (acceptability, adoption, cost, fidelity, penetration, and sustainability) and service outcomes (comprehensive services and timely service linkages); and (3) Assess WHC patient outcomes (effectiveness, satisfaction) at 6-month follow-up. Implementing an evidence-based intervention in usual care settings to reach more vulnerable AOD-using women who are HIV+ has potentially high public health impact if it can be implemented successfully and shown to be effective and sustainable in these new settings.