Project Description

The Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-Be (NuMoM2b), which began in 2010, studied pregnant women who were delivering for the first time (nulliparous women). The “Longitudinal Study of Loss of Imprinting in the First Trimester CVS Samples Compared to Placental Samples at Delivery” evaluated the underlying, interrelated mechanisms of several common adverse pregnancy outcomes, which can be unpredictable in women who have little or no pregnancy history to help guide their treatment. This initiative has addressed a critical group of at-risk women who are currently understudied and represent 40% of the four million births in the United States each year. As the data coordination center for the NuMoM2b study, RTI International collected and analyzed the data for this study. This responsibility specifically included setting up additional tracking in the data management system for chorionic villus samples specific to this sub study, incorporating data from the sub study into the primary database, constructing analysis files for the sub study, and data analysis. The results of this study helped inform health care providers and their patients who are pregnant or considering pregnancy and will support future research to improve care and outcomes in this group of women.

Project Partners
University of Indiana School of Medicine|NIH National Institution of Child Health and Human Development
Project Open
Closed
Countries