Recent epidemiologic studies suggest that women with adverse pregnancy outcomes (APOs), such as preeclampsia, are at increased risk for subsequent cardiovascular diseases. However, prospective data to elucidate the precise relationship between adverse pregnancy outcomes and subsequent cardiovascular disease are lacking. To address this critical knowledge gap, the National Heart, Lung, and Blood Institute (NHLBI), in collaboration with the Eunice Kennedy Shriver Kennedy National Institute of Child Health and Human Development, funded a follow-up study of expectant mothers to evaluate the association between APOs and maternal health approximately two years postpartum using prospectively and rigorously collected data and bio-specimens. This multicenter group is utilizing an ethnically, racially, socioeconomically and geographically diverse cohort of 10,000 nulliparous women enrolled in the NICHD-funded Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be. During the initial months of the project, RTI International helped develop the study protocol, consent forms, case report forms, study brochures, and other supporting documentation. RTI staff also developed data capture and data management systems during this same time period in preparation for enrollment.
Project Description
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Northwestern University|NIH National Heart, Lung, and Blood Institute
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Open
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