We propose to examine the short-term social, health and health care impacts of COVID-19 in a cohort of highly vulnerable women in the Bay Area of California. We are in a unique position to carry out this research expeditiously by leveraging an existing cohort of women with criminal justice system involvement from the parent study (NIMHD grant#R01 ).  The study population (N=370) is defined by several characteristics that are associated with vulnerability to COVID-19.  For example, 82% report one or more chronic health conditions, including 42% with respiratory conditions (eg, asthma COPD). Forty-nine percent are homeless and 24% are age 55 or older.  Furthermore, nearly three-quarters (72%) of women in the study are African American. Reports are rapidly emerging from multiple U.S. cities that African Americans are disproportionately affected by the virus.