The goal of the Nanofabric Pilot Study at RTI International is to assess the perceptions and acceptability of a new intravaginal drug delivery system for HIV prevention and contraception in the form of drug-eluting fibers fabricated by electrospinning and woven into a fabric. The project is taking place in Kampala, Uganda, Harare, Zimbabwe, and Durban, South Africa among up to 60 female participants of reproductive age who will join a focus group discussion. The intention of this study is to obtain general reactions (likes/dislikes, perceptions, possible use, etc.), and to probe a few key attributes (application, feel, geometry, etc.) about the intended fiber-based fabric as multipurpose technologies that can be explored in greater depth in future studies.